Tramadol
- Effective Pain Relief
- Dual Mechanism of Action
- Flexible Dosage Options
Product Information
Better health begins with the right choices.
Dr. G. Varbanov
General Medicine Doctor | UIN: 0400005105
Description
Tramadol is a strong pain reliever belonging to the class of opioid analgesics. It is primarily used for managing moderate to severe pain, particularly when other pain relief options are ineffective or not tolerated.
Tramadol works by altering how the brain perceives pain. It acts as an agonist of the μ-opioid receptor, which is crucial for pain relief. Additionally, tramadol inhibits the reuptake of serotonin and norepinephrine, neurotransmitters involved in pain modulation and mood regulation. This dual action helps in reducing pain perception and may also contribute to mood-enhancing effects. The active metabolite of tramadol, O-desmethyltramadol, is significantly more potent at the μ-opioid receptor, further enhancing its analgesic properties.
Tramadol is used for treating various types of pain, including postoperative pain, severe injuries, and chronic pain conditions such as osteoarthritis and rheumatoid arthritis. It is often prescribed when non-opioid pain relievers are insufficient or not tolerated.
Tramadol affects the body by interrupting pain signals between the brain and the body. It does not eliminate pain entirely but reduces its intensity. Unlike some other opioids, tramadol tends to cause less constipation, which is a common side effect of opioid medications. However, it can cause drowsiness and impair cognitive function, so caution is advised when performing activities requiring full alertness.
The benefits of using tramadol include its effectiveness in managing moderate to severe pain with a relatively lower risk of some side effects compared to stronger opioids. It is available in various forms, including immediate-release and extended-release forms, allowing for flexible dosing options. Tramadol is generally well-tolerated, though it carries risks of addiction and misuse like other opioids. Its ability to enhance mood through serotonin and norepinephrine modulation can also be beneficial for patients experiencing pain-related distress.
General Information
Tramadol is a strong pain reliever classified as an opioid analgesic. It is used to manage moderate to severe pain in adults. Tramadol works not only as an opioid agonist but also as a serotonin and norepinephrine reuptake inhibitor (SNRI), which enhances its pain-relieving effects.
Tramadol is primarily used for treating moderate to severe pain, including postoperative pain and chronic pain conditions, when other pain relief options are ineffective. It is often prescribed for pain that requires opioid-level management.
Tramadol works by binding to opioid receptors in the brain, altering how pain is perceived. Additionally, it inhibits the reuptake of serotonin and norepinephrine, which further enhances pain relief by activating descending pain inhibitory pathways.
The usual dose for adults is 50 to 100 mg every 4 to 6 hours for immediate-release forms, with a maximum daily dose of 400 mg. Extended-release forms are typically started at 100 mg once daily, with adjustments as needed.
Tramadol begins to work within about 30 minutes to an hour after taking an immediate-release form. Extended-release forms provide longer-lasting relief, starting within a few hours and lasting throughout the day.
If you miss a dose of Tramadol, take it as soon as you remember unless it is close to the time of your next dose. Do not double the dose to catch up.
Safety & Side Effects
Common side effects include dizziness, drowsiness, dry mouth, nausea, constipation, and headache. Serious side effects can include respiratory depression and addiction.
Yes, Tramadol can cause allergic reactions. Symptoms may include rash, itching, swelling, severe dizziness, or trouble breathing. If you experience any of these, seek medical attention promptly.
Tramadol can be used for long-term pain management but carries risks of dependence and addiction. Regular monitoring by a healthcare provider is necessary.
Yes, Tramadol can cause drowsiness and impair cognitive function. Avoid driving or operating machinery if affected.
Tramadol can interact with other medications, such as antidepressants, sedatives, certain pain relievers and medications for treating substance abuse.
Tramadol should be used with caution during pregnancy and breastfeeding. It can pass into breast milk and may affect the baby.
No, it is not recommended to drink alcohol while taking Tramadol. Alcohol can increase the risk of side effects such as drowsiness and impaired judgment.
Usage & Administration
Take Tramadol with a full glass of water. Extended-release forms should not be crushed or chewed.
Tramadol should not be taken by children under 12 years old, individuals with certain respiratory conditions, or those who have recently had a tonsillectomy or adenoidectomy. It should also be avoided by individuals with a history of substance abuse or individuals who are in the process of recovering from substance abuse.
Store Tramadol in a cool, dry place, out of reach of children and pets.
If you take too much Tramadol, seek emergency medical help immediately. Overdose symptoms can include difficulty breathing, drowsiness, and confusion.
You can take Tramadol with or without food. However, taking it with food may help reduce nausea.
No, do not break or crush extended-release Tramadol tablets or capsules. Immediate-release can be broken only in case there is no alternative.
Ordering & Delivery
Start your order for Tramadol by completing a health form or scheduling a doctor call. Once approved, the pharmacy takes care of the shipping.
Yes, you'll need a prescription to purchase Tramadol. Complete an online form or consult with a doctor to proceed.
Tramadol is usually delivered in 1–2 business days after the prescription is received by the pharmacy.
Due to legal pharmacy rules, Tramadol cannot be returned once dispensed. Be sure before confirming your order.
